Stress: An evolutionary mutagen

Schizophrenia: An Evolutionary Defense Against Severe Stress

The adrenochrome investigations into schizophrenia which I have pursued since 1952 and the recent important investigations into the relationship between heart function and (adrenalin —> adrenochrome) points to a connection between brain and cardiac disorder. I suggest there is a link between schizophrenia and some types of heart dysfunction. My hypothesis is that the biochemistry of schizophren...

Chemical Mutagen Effect on Physiological Properties of Stevia rebaudiana Bertoni under Salt Stress

The present study was performed to evaluate the effects of different concentrations of ethyl methane sulfonate (0, 0.1, 0.2 and 0.5%) on some physiological characteristics of regenerated plants from calli of stevia at 30, 60 and 120 min under various levels of salinity stress (0, 50 and 100 mM of NaCl). This experiment was carried out based on completely randomized two-factorial designs with th...

Alpha radiation is a major germ-line mutagen over evolutionary timescales

Question: Is alpha radiation responsible for major changes in genome structure, including karyotypic change and higher ploidy? In vitro, high doses of alpha radiation yield many chromosomal changes, while low doses yield mostly point mutations. Data description: Previously published data on karyotypic variability and the incidence of polyploidy in various animal and plant species. Search method...

T-DNA as an insertional mutagen in Arabidopsis.

Why is stress so deadly? An evolutionary perspective.

The reaction of the body to prolonged stress has many harmful effects. Classical theory assumes that stress responses have evolved due to their short-term selective advantages ('flight or fight'), and despite their adverse long-term effects. In contrast, we demonstrate that the adverse effects of stress responses may have a selective advantage. Using an analytical model we show that a gene that...